{"id":60813,"date":"2026-03-06T17:34:26","date_gmt":"2026-03-06T12:04:26","guid":{"rendered":"https:\/\/www.wbcil.com\/liposomal-ferrous-ascorbate\/"},"modified":"2026-08-27T18:37:12","modified_gmt":"2026-08-27T13:07:12","slug":"liposomales-eisenascorbat","status":"publish","type":"post","link":"https:\/\/www.wbcil.com\/de\/liposomale-technologie\/liposomales-eisenascorbat\/","title":{"rendered":"Liposomales Eisenascorbat"},"content":{"rendered":"

Liposomales Eisen(II)-Ascorbat ist eine in Phospholipide eingekapselte Formulierung, die f\u00fcr eine optimale orale Eisenverabreichung bei der Behandlung von Eisenmangelan\u00e4mie entwickelt wurde. Es besteht aus Eisen(II)-Ascorbat \u2013 Fe\u00b2\u207a, chelatisiert mit Ascorbins\u00e4ure (Vitamin C) \u2013, das in Phospholipid-Doppelschichten eingeschlossen ist und Liposomen bildet (typischerweise mit einem Durchmesser von h\u00f6chstens 220 nm). Die Endformulierung des liposomalen Produkts erscheint als trockenes, br\u00e4unliches Pulver. Das Produkt hat keinen starken Geruch und weist keine metallischen Noten auf, wie sie \u00fcblicherweise mit freiem Eisen in Salzform assoziiert werden.<\/p>\n

Ascorbins\u00e4ure stabilisiert Fe\u00b2\u207a, verhindert so dessen Oxidation zu einer weniger gut resorbierbaren Eisenform (Fe\u00b3\u207a) und verbessert die Eisenaufnahme im Darm \u00fcber Vitamin-C-<\/strong><\/a>abh\u00e4ngige Transportwege. Die liposomale Struktur sch\u00fctzt das Eisen zudem vor dem Abbau im Magen, vor Hemmstoffen in der Nahrung (wie Phytaten und Polyphenolen) sowie vor direkter Reizung der Darmschleimhaut. Die Bioverf\u00fcgbarkeit dieser Formulierung liegt im Allgemeinen bei \u00fcber 80 %, verglichen mit 10\u201315 % bei herk\u00f6mmlichen Eisen(II)-Salz-Formulierungen.<\/p>\n

Die liposomale Formulierung weist eine m\u00e4\u00dfige Hygroskopizit\u00e4t auf, daher sollte das Pulver in einem feuchtigkeitsbest\u00e4ndigen Beh\u00e4lter gelagert werden, um Verklumpen oder Agglomeration zu verhindern; aufgrund der Lipidverkapselung ist diese Formulierung jedoch (bei Lagerung in Pulverform) weniger feuchtigkeitsempfindlich als nicht-liposomales Eisen(II)-Ascorbat.<\/p>\n","protected":false},"excerpt":{"rendered":"

Liposomales Eisen(II)-Ascorbat ist eine in Phospholipide eingekapselte Formulierung, die f\u00fcr eine optimale orale Eisenverabreichung bei der Behandlung von Eisenmangelan\u00e4mie entwickelt wurde. Es besteht aus Eisen(II)-Ascorbat \u2013 Fe\u00b2\u207a, chelatisiert mit Ascorbins\u00e4ure (Vitamin C) \u2013, das in Phospholipid-Doppelschichten eingeschlossen ist und Liposomen bildet (typischerweise mit einem Durchmesser von h\u00f6chstens 220 nm). Die Endformulierung des liposomalen Produkts erscheint … Continue reading „Liposomales Eisenascorbat“<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":60816,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[328,458,339],"tags":[],"class_list":["post-60813","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-eisen","category-liposomale-nutrazeutika","category-liposomale-technologie"],"acf":[],"yoast_head":"\nLiposomales Eisenascorbat | Bioverf\u00fcgbarkeit von \u00fcber 80 %<\/title>\n<meta name=\"description\" content=\"Liposomales Eisenascorbat (C12H14FeO12, 406,08 g\/mol) mit >80 % Bioverf\u00fcgbarkeit und einer Gr\u00f6\u00dfe von \u2264220 nm.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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