{"id":60869,"date":"2026-03-06T17:34:26","date_gmt":"2026-03-06T12:04:26","guid":{"rendered":"https:\/\/www.wbcil.com\/liposomal-ferrous-ascorbate\/"},"modified":"2026-08-29T11:15:45","modified_gmt":"2026-08-29T05:45:45","slug":"liposomaal-ijzerascorbaat","status":"publish","type":"post","link":"https:\/\/www.wbcil.com\/nl\/liposoomtechnologie\/liposomaal-ijzerascorbaat\/","title":{"rendered":"Liposomaal ijzerascorbaat"},"content":{"rendered":"

Liposomaal ijzer(II)ascorbaat is een met fosfolipiden ingekapselde formulering die is ontwikkeld voor een superieure orale ijzeropname bij de behandeling van bloedarmoede door ijzertekort. Het bestaat uit ijzer(II)ascorbaat \u2014 Fe\u00b2\u207a in chelaatvorm met ascorbinezuur (vitamine C) \u2014 dat is ingekapseld in fosfolipide dubbellaagjes die liposomen vormen (doorgaans met een diameter van maximaal 220 nm). De uiteindelijke formulering van het liposomale product ziet eruit als een droog, bruinachtig poeder. Het product heeft geen sterke geur en vertoont geen metaalachtige bijsmaken die vaak worden geassocieerd met vrij ijzer in zoutvorm.<\/p>\n

Ascorbinezuur stabiliseert Fe\u00b2\u207a, waardoor wordt voorkomen dat het oxideert tot een minder goed opneembare vorm van ijzer (Fe\u00b3\u207a) en waardoor de opname van ijzer in de darmen via vitamine C<\/strong><\/a>-afhankelijke transportroutes wordt bevorderd. De liposomale structuur beschermt het ijzer tevens tegen afbraak in de maag, tegen remmende stoffen in de voeding (zoals fytaten en polyfenolen) en tegen directe irritatie van het slijmvliesoppervlak van de darm. De biologische beschikbaarheid van deze formulering ligt over het algemeen boven de 80%, vergeleken met 10-15% voor conventionele formuleringen met ijzerzout.<\/p>\n

De liposomale formulering heeft een matige hygroscopiciteit, dus het poeder moet worden bewaard in een vochtbestendige verpakking om samenklontering of agglomeratie te voorkomen; deze formulering is echter ook minder vochtgevoelig (bij opslag in poedervorm) dan niet-liposomaal ijzerascorbaat vanwege de inkapseling in lipiden.<\/p>\n","protected":false},"excerpt":{"rendered":"

Liposomaal ijzer(II)ascorbaat is een met fosfolipiden ingekapselde formulering die is ontwikkeld voor een superieure orale ijzeropname bij de behandeling van bloedarmoede door ijzertekort. Het bestaat uit ijzer(II)ascorbaat \u2014 Fe\u00b2\u207a in chelaatvorm met ascorbinezuur (vitamine C) \u2014 dat is ingekapseld in fosfolipide dubbellaagjes die liposomen vormen (doorgaans met een diameter van maximaal 220 nm). De uiteindelijke … Continue reading “Liposomaal ijzerascorbaat”<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":60872,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[429,456,440],"tags":[],"class_list":["post-60869","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ijzer","category-liposomale-nutraceuticals","category-liposoomtechnologie"],"acf":[],"yoast_head":"\nLiposomaal ijzerascorbaat | >80% biologische beschikbaarheid<\/title>\n<meta name=\"description\" content=\"Lees meer over liposomaal ijzerascorbaat (C12H14FeO12, 406,08 g\/mol) met \u2264220 nm grootte en >80% biologische beschikbaarheid.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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