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ABSTRACT The effectiveness of intravenous ferric carboxymaltose (FCM) in quickly increasing normal hemoglobin concentration and replenishing body iron reserves up to 6–12 wk is known; however, its long-term effectiveness is unknown. In this study conducted in northern India during August...
Read moreAbstract Background Perioperative anemia is common in cardiac surgery. Few studies investigated the effect of postoperative intravenous (IV) iron supplementation and were mostly inconclusive. Methods Design: A randomized single-center, double-blind, placebo-controlled, parallel-group trial. Participants: 195 non-anemic patients were recruited from...
Read moreAuthor links open overlay panel Nanja Bevers MD 1, Els Van de Vijver PhD, MD 2, Arta Aliu 1, Ashkan Rezazadeh Ardabili MD 3, Philippe Rosias MD, PhD 1, Janneke Stapelbroek MD, PhD 4, Imke A. Bertrams Maartens MD 5,...
Read moreAbstract Introduction: Iron deficiency (ID) is associated with worse outcomes in patients with heart failure (HF). In adults with HF and ID, intravenous (IV) iron replacement therapy (IRT) improves HF outcomes and is the first-line therapy for ID because oral...
Read moreBackground: Iron deficiency is common in patients with heart failure (HF) and is associated with reduced exercise capacity and poor outcomes. Whether correction of iron deficiency with (intravenous) ferric carboxymaltose (FCM) affects peak oxygen consumption [peak VO2], an objective measure...
Read moreIntroduction: PAH is a progressive disease with limited prognosis. Iron deficiency (ID) correlates in PAH patients with disease severity and mortality. Oral iron resorption is impaired by hepcidine in PAH. In a former pilot study, we could demonstrate a short-term...
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