Nicorandil

Nicorandil (C8H9N3O4) is a pharmaceutical drug that is used to treat angina pectoris, a condition characterized by chest pain or discomfort caused by reduced blood flow to the heart. It works by relaxing and dilating the blood vessels, which improves blood flow to the heart and reduces the workload on the heart.

Trusted Nicorandil Suppliers in India

This element has the chemical formula C8H9N3O4 and a molecular weight of 211.17 g/mol. It is a nitrate ester of nicotinamide and is structurally related to potassium channel openers. It is also known by its CAS number, 65141-46-0. Nicorandil is also known by other names such as SG-75, IKorel, and Nicodec.

West Bengal Chemical Industries Limited is one of the best Nicorandil manufactures in India. It is available in tablet form for oral administration. It is a white to slightly yellowish powder with a faint odor and a bitter taste. It is soluble in water and slightly soluble in ethanol. Nicorandil is a vasodilator, which means that it widens the blood vessels to improve blood flow. It is also a potassium channel opener, which means that it enhances the movement of potassium ions across the cell membrane to promote relaxation of smooth muscle cells.

Molecular Formula – C₈H₉N₃O₄

Molecular Weight – 211.175 gm/mol

CAS No – 65141-46-0

Shelf Life – 36 months

HSN Code –

Packing Size –

Storage Condition – Keep Well Closed, protected against light, dry and at room temperature

Additional Info –

#	PARAMETER	SPECIFICATION
1.	Description	A white to off white powder.
2.	Identification a) IR b) HPLC	a) IR of the sample should match with the IR of the standard. b) The retention time of the principal peak in the chromatogram obtained with the test solution corresponds to the principal peak in the chromatogram obtained with the reference solution.
3.	Water Content ( By KF )	NMT 0.3% w/w
4.	Heavy Metal	NMT 20.0 ppm
5.	Sulphates	NMT 0.04%
6.	Sulphated Ash	NMT 0.1% w/w
7.	Related Substances (a)Individual Impurity (b)Total Maximum Impurities	a) NMT 0.2% b) NMT 0.6%
8.	Assay by HPLC (On Anhydrous Basis)	98.0% -102.0 % w/w

Treatment of angina: Nicorandil is used as a first-line treatment for stable angina, a type of angina that occurs during physical exertion or emotional stress. It works by relaxing and dilating the blood vessels, which improves blood flow to the heart and reduces the workload on the heart.

Heart disease: Nicorandil is also used to treat other heart-related conditions, such as heart failure, myocardial infarction, and hypertension.

Peripheral arterial disease: Nicorandil is sometimes used to treat peripheral arterial disease, a condition in which the arteries in the legs become narrow or blocked, causing pain and discomfort.

Research: Nicorandil is also used in research studies to investigate its potential in the treatment of other medical conditions, such as stroke and diabetes.