Potassium Bisglycinate

Potassium Biglycinate, also known as Potassium glycinate, is a salt of glycine and potassium. It is a white, crystalline powder with a slightly bitter taste. It can be represented by the chemical formula K(C6H13NO2)2, where each molecule of glycine is combined with two potassium ions.

According to the International Union of Pure and Applied Chemistry (IUPAC) nomenclature, the correct name for Potassium Biglycinate is Potassium bis[(2S)-2-amino-2-(2-amino-1,3-dicarboxamido)ethyl] ester.

Potassium Biglycinate is commonly used as a chelating agent, which means it can bind to and remove metal ions from a solution. It is also used as a nutrient supplement, as glycine is an essential amino acid.

As per the current report, it is not currently approved by the US Food and Drug Administration (FDA) for any specific indications. However, it has been used in some dietary supplement products for its potential benefits in supporting muscle health, improving sleep quality, and reducing inflammation.

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Sli No.	TESTS PARAMETERS	SPECIFICATION	RESULTS
1.	Description	Off white to light yellowish crystalline powder	Light yellowish crystalline powder
2.	Solubility	Soluble in water	Soluble in water
3.	pH (of 1% aqueous suspension)	7.0 -9.0
4.	Density	0.85 – 1.35 gm/cc	Tapped Density : 0.86 gm/cc
5.	Arsenic	NMT 2.0 ppm	< 2.0 ppm
6.	Lead	NMT 10.0 ppm	< 10.0 ppm
7.	Cadmium	NMT 1.0 ppm	< 1.0 ppm
8.	Mercury	NMTO.I ppm	< 0.1 ppm
9.	LOD (at 105 ⁰C for 4 hours)	NMT 8.0%w/w	2.95% w/w
10.	Potassium Content ( On Dried Basis)	NLT 20.0% w/w	20.15% w/w
11.	Total Plate Count	NMT 1000 cfu/gm	< 1000 cfu/gm
12.	Total Yeast & Mould	NMT 100 cfu/gm	< 100 cfu/gm
13.	Coliform	NMT 10 cfu/gm	< 10 cfu/gm
14.	Staphylococcus aureus	Absent	Absent
15.	E.coli	Absent	Absent
16.	Salmonella	Absent/ 25 gm	Absent

Pharmaceutical uses:

It is important to note that the safety and effectiveness of Potassium Biglycinate as a supplement have not been thoroughly studied and it is always best to consult a healthcare provider before taking any new supplement.

Nutrient supplementation: Potassium Biglycinate can be used as a source of potassium and glycine in patients who are deficient in these nutrients.

Heavy metal poisoning treatment: Potassium Biglycinate’s chelating properties make it useful for removing harmful metal ions from the body and treating heavy metal poisoning.

Inflammation reduction: Some studies have shown that glycine, a component of Potassium Biglycinate, has anti-inflammatory effects, making it a potential candidate for the treatment of inflammatory disorders.

Metal chelation

Potassium Biglycinate is a chelating agent, meaning it can bind to metal ions and remove them from a solution. This property makes it useful for removing harmful metal ions from the body and for treating heavy metal poisoning.

Animal feeds uses:

Potassium Biglycinate is particularly useful for ruminants, poultry, and swine, which are known to have lower potassium utilization from traditional inorganic sources. The addition of Potassium Biglycinate to animal feed can help improve growth rates, feed efficiency, and overall health in livestock.

Medical uses:

Potassium Biglycinate is used as a dietary supplement in the medical industry. It is used to address potassium deficiencies in individuals and to support normal electrolyte balance in the body. Potassium is an essential mineral that is involved in several critical functions, including maintaining fluid and electrolyte balance, supporting proper muscle and heart function, and aiding in the transmission of nerve impulses.