Sodium Butyrate

Sodium Butyrate

Sodium Butyrate is a sodium salt of butyrate which has antineoplastic properties. Butyrate is a short-chain fatty acid that bonds together with zinc sites of class I and II histone deacetylases competitively (HDACs).

This bond can affect histone hyperacetylation, which can modify DNA conformation and lead to chromatin uncoiling or relaxing. It can increase chromatin accessibility to transcription-regulatory complexes that can repress cell cycle-related genes. It can also affect the proteome and gene expression pathways in body cells.

India’s Leading Sodium Butyrate Supplier

Usually, Sodium Butyrate is used in pharmaceutical drugs to help with the passive absorption of water in the colon. It can affect

cognitive function in Schizophrenia. Sodium Butyrate can also be used in food consumption as an additive to prevent colon cancer in animals.

WBCIL is one of the top leading sodium butyrate manufacturers in India that provides this pharmaceutical drug at market sodium butyrate price.

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Molecular Formula – C4H7NaO2

Molecular Weight – 10.09 gm/mol

CAS No – 156-54-7

Shelf Life – 36 months

HSN Code –  2915.6010

Packing Size – 20/25 kg in HDPE bag/drum

Storage Condition – Keep Well Closed, protected against light, dry and at room temperature

Sl. No. PARAMETER SPECIFICATION
1. Description White free flowing powder, with occasional friable lump, odour characteristic.
2. Solubility Soluble in water
3. Identification Positive for Sodium & Butyric Acid.
4. pH (of 10% solution in water) 7.0 – 11.0
5. Heavy Metals (as Lead) NMT 10 ppm
6. Arsenic NMT 3 ppm
7. LOD (at 105°C till constant weight) NMT 3.0% w/w
8. Assay (On Dried Basis) 98.0% w/w – 101.0% w/w
Category Description
Process Regulator Sodium Butyrate works as an accelerator, activator, oxidation agent, reducing agent, etc.
Manufacturing It can be used in manufacturing papers.
Bio Chemistry HDAC (Histone Deacetylase Inhibitor).
Drugs
  • Used as a dietary supplement to improve passive absorption of water in the colon.
  • Helps with memory function in an Alzheimer’s disease mouse model.
  • Sodium Butyrate is also used as a treatment for Irritable Bowel Syndrome (IBS) & Crohn’s Disease. As well it can induce Pancreatic Progenitor formation.
  • Works as a component in homogenization and immunoprecipitation buffer for HDAC inhibition in fly embryos and insect s2 cells.
  • Can be used as a histone deacetylase inhibitor in breast cancer cell line MDA-MB-231.
Feed Additives Can be used as a food additive for animals to provide nutrition. It can help to prevent Colon Cancer in animals.
Food Sodium Butyrate has a high fungus-killing rate and low toxicity that can help in agriculture to produce more healthy fruits and vegetables.
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