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Product Name:
Liposomal Curcumin
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Molecular Formula:
C21H20O6
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Molecular Weight:
368.4 g/mol
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CAS No.:
458-37-7
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HSN Code:
13021919
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CID Code:
969516
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Shelf Life:
3 years
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DrugBank ID
DB11672
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UNII No.
IT942ZTH98
- USP
- IUPAC Names
- Synonyms
- Insights
USP of Liposomal Curcumin
- Liposomal curcumin protects curcuminoids with phospholipids for better absorption.
- Nanoscale liposomes improve gut barrier penetration.
- It boosts bioavailability without piperine.
- Liposomes merge quickly with cell membranes.
- Encapsulation prevents curcuminoid oxidation.
- High bioavailability makes small doses effective.
IUPAC Names of Liposomal Curcumin
(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
Synonyms of Liposomal Curcumin
- Diferuloylmethane
- curcumin
- 458-37-7
- Natural yellow 3
- Curcuma
- Curcumin I
- Souchet
- Haidr
- Halad
- Halud
- Yellow Ginger
- (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
- C.I. Natural Yellow 3
- Yellow puccoon
- Golden seal
- Diferaloylmethane
- Curcumine
- Hydrastis
- Tumeric yellow
- CI Natural Yellow 3
- Kurkumin
- Curcumin (synthetic)
- Zlut prirodni 3
- Jianghuangsu
- Zlut prirodni 3
- Cucurmin
- 94875-80-6
- Tumeric oleoresin
- (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
- NSC 32982
- 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
- CCRIS 3257
- CHEBI:3962
- Curcurmin
- Lipocurc
- Kurkum
- 1,5-Di(vanillyliden)acetylaceton
- CI 75300
- NCI-C61325
- 1,5-Divanillyliden-2,4-pentandion
- UNII-IT942ZTH98
- Curcumin e100
- NSC 687842
- trans,trans-Curcumin
- BRN 2306965
- IT942ZTH98
- 1,9-Bis(4-hydroxy-3-methoxyphenyl)-2,7-nonadiene-4,6-dione
- 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E,E)-
- 1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
- CHEMBL140
- NSC-687842
- (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
- SMR000058237
- 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-
- DTXCID901421
- 4-08-00-03697 (Beilstein Handbook Reference)
- 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
- curouma
- NCGC00017159-05
- kachs haldi
- 2,7-Nonadiene-4,6-dione, 1,9-bis(4-hydroxy-3-methoxyphenyl)-
- safra d’inde
- (1E,6E)-1,7-bis(4-hydroxy-3-methoxy-phenyl)hepta-1,6-diene-3,5-dione
- (1E,6E)-1,7-bis[4-hydroxy-3-(methyloxy)phenyl]hepta-1,6-diene-3,5-dione
- Tumeric
- 1,7-BIS-(4-HYDROXY-3-METHOXYPHENYL)-HEPTA-1,6-DIENE-3,5-DIONE
- CAS-458-37-7
- Phytosome, CurcuminCCRIS 5804
- C Yellow 15
- SR-01000000149
- Curcumin (Standard)
- Curcumin, analytical standard
- MLS001148449
- cid_969516
- Curcumin, >=94% (curcuminoid content), >=80% (Curcumin)
- 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadien-3,5-dione
- 1,7-bis(4-hydroxy-3-methoxyphenyl)1,6-heptadiene-3,5-dione
- Curcumin, matrix substance for MALDI-MS, >=99.5% (HPLC)
- Curcumin, United States Pharmacopeia (USP) Reference Standard
- 1,7-BIS(4-HYDROXYMETHOXYPHENYL)-1,6-HEPTADIENE-3,5-DIONE
- 1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione
- 1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
- ((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione)
- (1E,6E)-1,7-bis(3-methoxy-4-oxidanyl-phenyl)hepta-1,6-diene-3,5-dione
- (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione #
- (1E,6E)-1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione
- (1Z,6E)-1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione
- 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, (E,E)-
- 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one
- 5-Hydroxy-1,7-bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,4,6-trien-3-one
- Curcumin; 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
- (1E,4Z,6E)-5-Hydroxy-1,7-bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,4,6-trien-3-one
- 207-280-5
Insights Liposomal Curcumin
- Appearance: Yellow to orange viscous liquid or dry powder (customized form)
- Solubility: Water-dispersible (liposomal form)
- Stability: Highly stable under GMP storage conditions
- Formulation Type: Liposomal Suspension / Powder
- Particle Size: 100-200 nm
- pH: 6.0 – 7.5
- storage temp: 2-8°C
- Storage Conditions: Store in a cool, dry place, away from light
- Odor: Mild, slightly earthy odor
- Taste: orange taste
- Packaging: Food-safe HDPE drums, glass bottles, or sachets
Description of Liposomal Curcumin
Liposomal curcumin is a next-generation pharmaceutical-grade liposomal curcumin delivery system in which curcumin, extracted from Curcuma longa L. at ≥95% curcuminoid purity, is encapsulated as encapsulated curcumin liposomes with a phospholipid bilayer structurally identical to human cell membranes. WBCIL’s liposomal curcumin is available as a supplier-grade API for nutraceutical and pharmaceutical manufacturers, supplied as bulk liposomal curcumin wholesale powder or finished liposomal curcumin OEM format to brands in 30+ countries.
Available Forms
Supplied as bulk liposomal turmeric curcumin powder, liposomal curcumin capsules, softgel-compatible liquid suspension, and finished private label product. EE% exceeds 85%, confirmed by HPLC across all commercial batches.
Application of Liposomal Curcumin
- Anti-Inflammatory & Joint Health: Used in oral formulations for joint discomfort, arthritis-associated inflammation, and post-exercise recovery, delivering effective plasma concentrations at lower doses than conventional extracts.
- Metabolic & Liver Support: Supports healthy glucose and lipid metabolism and contributes to normal liver function through curcumin’s modulation of NF-κB and COX-2 pathways.
- Cognitive & Neurological Support: Enhanced blood-brain barrier permeability via liposomal curcumin phospholipid encapsulation supports formulations targeting cognitive health and neuroprotection.
- Joint & Anti-Inflammatory Supplements: Clean-label, plant-derived ingredient for premium joint support liposomal curcumin capsules and stick-packs targeting active adults and ageing demographics.
- Skin Health & Beauty-from-Within: Supports skin barrier function, collagen integrity, and reduction of oxidative stress-driven pigmentation for beauty supplement lines.
- Functional Beverages & Fortification: Cold water dispersibility makes WBCIL’s high-quality liposomal curcumin suitable for fortified beverages and powder sachet formats without sedimentation.
- Sports Recovery: Included in post-workout formulations for exercise-induced inflammation management and muscle recovery support.
- Topical Serums & Creams: The phospholipid bilayer mirrors the composition of skin cell membranes, enabling transdermal penetration of anti-inflammatory serums and brightening creams.
- Veterinary Supplements: Used in joint health and anti-inflammatory formulations for companion animals and livestock.
Liposomal Technology & Delivery Science
Liposomes encapsulate actives within a phospholipid bilayer mirroring natural cell membranes. For curcumin, which is inherently insoluble and rapidly metabolised, phospholipid encapsulation in liposomes is the mechanism that enables viable oral dosing.
Phospholipid Architecture
90%+ phosphatidylcholine and phosphatidylethanolamine from non-GMO sunflower lecithin. Consistent fatty acid profile, soy-free, clean-label compliant. Enables endocytic uptake bypassing transporter saturation and passive diffusion limitations.
Vesicle Engineering
100–200nm vesicles, PDI ≤0.25, zeta potential ≥±30mV. Engineered for consistent liposomal curcumin bioavailability, colloidal stability across GI transit, and batch-to-batch reproducibility for OEM supply.
Analytical Compliance
EE% by HPLC, ICH Q1A/Q1B stability, DLS, FTIR, DSC, CoA per batch. Full regulatory documentation for FDA, EMA, CDSCO, and FSSAI submissions.
Liposomal Curcumin vs Traditional Curcumin
| Parameter | WBCIL Liposomal Curcumin | Traditional Curcumin Extract |
|---|---|---|
| Absorption Mechanism | Endocytosis and lymphatic uptake | Passive diffusion, solubility-limited |
| Bioavailability | High, lipid-mediated, bypasses phase II metabolism | Low to moderate, rapidly metabolised and excreted |
| Effective Dose | Lower dose for equivalent plasma concentration | 4-8g/day with diminishing returns above threshold |
| GI Tolerability | Minimal, curcumin shielded from gastric contact | GI irritation and nausea at therapeutic doses |
| Aqueous Solubility | Cold water dispersible | Insoluble, restricts beverage and food use |
| Oxidative Stability | High, protected within phospholipid bilayer | Susceptible to oxidative degradation |
OEM, Private Label & Bulk Ingredient Supply
WBCIL is a WHO-GMP and cGMP-certified liposomal curcumin manufacturer and liposomal curcumin bulk supplier, providing pharmaceutical-grade liposomal curcumin wholesale to nutraceutical brands, liposomal curcumin OEM supplement manufacturers, and liposomal curcumin private label buyers across 30+ countries. Trusted by 4,000+ clients globally as a reliable liposomal curcumin API supplier.
Contract Manufacturing
End-to-end liposomal curcumin contract manufacturing with batch CoA, ICH stability data, HPLC-verified EE%, and complete regulatory dossiers. Custom curcumin load, particle size, and phospholipid blend available.
Private Labelling in 30+ Countries
Available as a private-label liposomal curcumin with flexible MOQ. Custom packaging and label design with full regulatory documentation. Backed by 64 years of pharmaceutical formulation expertise.
Bulk Ingredient Supply
WHO-GMP-certified liposomal curcumin bulk supplier; bulk liposomal curcumin wholesale powder in food-safe HDPE drums to commercial-scale orders. Full CoA, MSDS, specification sheet, and stability data with every shipment.
Engineering Precision in WBCIL’s Liposomal Systems
| Parameter | WBCIL Liposomal Curcumin | Ordinary Liposomal Curcumin |
|---|---|---|
| Phospholipid Source | >90% PC+PE, non-GMO sunflower lecithin | Low-grade lecithin, variable PC, often soy-derived |
| Vesicle Size Control | 100–200nm, PDI ≤0.25, batch-consistent | Inconsistent sizing, broad particle distribution |
| Electrostatic Stability | Zeta ≥±30mV, prevents aggregation | Aggregation-prone, poor shelf stability |
| Encapsulation Efficiency | ≥85% EE%, HPLC verified per batch with CoA | EE% undocumented in most commodity products |
| Manufacturing Process | Patented solvent-free, GMP-compliant — no heat or alcohol | Heat or solvent-based — degrades curcumin structure |
Sourcing Liposomal Curcumin from WBCIL
- Manufacturing Legacy: 64+ years of pharmaceutical API and liposomal manufacturing experience across India’s most regulated facilities.
- Patented Science: 17 active patents including a patented solvent-free green liposomal process preserving polyphenol integrity through encapsulation.
- Global Reach: Trusted by 4,000+ clients, liposomal curcumin OEM manufacturers, pharmaceutical formulators, and private label brands across 30+ countries.
- Award Recognised: National IP Award 2024, India’s Top MSME for Patent Filing and Commercialisation, Ministry of Commerce & Industry.
- Certified Compliance: WHO-GMP, cGMP, ISO, HACCP, and FSSAI certified. USFDA guideline-maintained production with full dossier support for international submissions.
Liposomal curcumin encapsulates pharmaceutical-grade curcumin within encapsulated curcumin liposomes, enabling uptake via endocytosis rather than passive diffusion. This bypasses the solubility and metabolism barriers that limit conventional curcumin to only 22-41 ng/mL in plasma, even at 8g daily doses
WBCIL brings 64+ years of pharmaceutical manufacturing experience, 17 active patents including a solvent-free green liposomal process, and WHO-GMP, cGMP, ISO, and HACCP certifications. Every batch is HPLC-verified at ≥85% EE% with a batch-specific CoA, trusted by 4,000+ clients across 30+ countries.
EE% ≥85% by HPLC, particle size 100–200nm by DLS, PDI ≤0.25, and zeta potential> ±30 mV verified per batch. ICH Q1A/Q1B stability studies, FTIR, and DSC analysis conducted with full CoA documentation available on request.
The phospholipid bilayer prevents curcumin from direct contact with the gastric tract, thereby eliminating the nausea and GI irritation associated with high-dose conventional curcumin. Most is absorbed via endocytosis before reaching the colon.
Bulk liposomal curcumin wholesale powder (1kg–1000kg), liposomal curcumin capsules, softgel-compatible suspension, and finished liposomal curcumin private label. Liposomal curcumin contract manufacturing with custom specifications available. Flexible MOQs with export to 30+ countries.
