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Role of Calcium Butyrate in nutraceutical supplements
Published on: September 27, 2023

Role of Calcium Butyrate in nutraceutical supplements

Importance of Calcium

Throughout human life, calcium is an important mineral for bone health. Calcium supplements might be an option for the source of calcium in the human body, although the diet is the best way of obtaining calcium.

However, the type of supplement to be chosen, the pros and cons of calcium supplements, and the amount of calcium needed for the human body should be thoroughly analyzed before considering calcium supplementation. For the proper functioning of the nerves, muscles, and heart alongside maintaining and building strong bones, the human body needs calcium.

  • High blood pressure, diabetes, and cancer can be also prevented by the supplementation of calcium along with Vitamin D which can have benefits beyond bone health.
  • External sources of calcium are required since the human body does not produce
  • Calcium-fortified beverages and foods such as milk substitutes fruit juices cereals and soy products, fish with edible soft bones such as canned salmon and sardines, dark green leafy vegetables such as kale and broccoli, and dairy products such as yogurt, milk, and cheese a sum of the various foods through which calcium can be obtained in the regular diet.
  • Vitamin D is extremely important for the absorption and proper utilization of calcium. Vitamin D can be found in yolks and canned salmon with bones.
  • Vitamin D can also be obtained from fortified foods and sun exposure. However, individuals with certain bowel or digestive disorders, such as celiac disease or inflammatory bowel disease, that affect calcium absorption, as well as those undergoing long-term corticosteroid treatment, consuming excessive amounts of protein or sodium, limited dairy intake or lactose intolerance, and those following a vegan diet, may have difficulty obtaining adequate calcium despite following a balanced and healthy diet.

Calcium supplements a generally recommended in these situations which can help to meet that individual’s calcium requirements.

However, before taking calcium supplements a doctor or a medical expert should always be consulted.

Role of Calcium Butyrate in nutraceutical supplements

What is Calcium Deficiency?

An overall feeling of sluggishness, lack of energy, and even insomnia can result from low levels of calcium causing extreme fatigue. Characterized by confusion, forgetfulness, and a lack of focus, fatigue associated with a Calcium deficiency is also known to involve brain fog, dizziness, and lightheadedness.

  • Psoriasis, skin inflammation or eczema which can lead to dry or itchy patches, alopecia which causes hair to fall out in patches, coarse hair, brittle, broken, or parched nails, and dry skin are some of the symptoms of low levels of calcium affecting the skin and nail of an individual. People who do not eat dairy and postmenopausal people are at the highest risk of facing the problem of calcium deficiency.
  • The risk of getting a fracture increases as the bones are weakened over time due to calcium deficiency in the human body. In order to keep blood levels up the human body uses Calcium from the bones when an individual does not consume enough Calcium from outside sources such as supplements or food. This can also lead to calcium deficiency due to the calcium present in the bones getting used up.
  • When the calcium content in the human blood becomes very low, a disease caused by calcium deficiency might kick in which is known as hypocalcemia. Alterations in the brain, cataracts, dental changes, and osteoporosis which might lead to brittle bones, can be caused by a long-term calcium deficiency.
  • Though there are no early symptoms shown by calcium deficiency, it still might become life-threatening without treatment over a long period of time. Health problems such as using certain medications like diuretics, the removal of the stomach, and kidney failure are some of the primary causes of calcium deficiency.
  • Tingling and numbness in the legs, feet, arms, and hands and as well as around the mouth, pain in the arms and the thighs when moving or walking, and spasms, cramps, and muscle aches are some of the muscle problems that arise due to calcium deficiency. These problems, if kept untreated, might lead to severe conditions like arrhythmias, convulsions, or even death.

Risks related to Calcium supplementation

Calcium supplements should be avoided if an individual has health conditions that cause excess calcium in the bloodstream which is known as hypercalcemia. Thus calcium supplementation should be only done with the consultation and supervision of a medical expert or doctor.

Heart disease and high dosage of calcium supplements are suspected to be interrelated but have not been proven to be definite. To know the effect of calcium supplements on heart attack risk evidence and research have a major shortcoming before doctors can conclude anything. Prostate cancer and Calcium supplementation have also been linked in some way which has given rise to a similar controversy.

Recent studies have shown no increased risk of prostate cancer associated with total calcium, supplementary calcium, and dietary calcium intake, although some studies in the past have shown that high calcium intake from dairy products and supplements might increase the risk of prostate cancer.

However, excessive amounts of calcium should always be avoided and the dosage should be measured very carefully until and unless more is known about the possible risks of high-dose calcium intake. It is important to talk to a medical expert or a doctor to determine the right supplementation of calcium for an individual which is related to any health issue.

Definition of Calcium Butyrate

Butyrate provides up to 90% of the energy requirements of the cells that line the gut of the human body, known as colonocytes, acting as their main fuel.

Butyrate helps in the enhancement of the immunity power in the cells present in the gut. By suppressing the activity of specific immune cells, Butyrate functions as an “HDAC inhibitor”, meaning that it performs anticancer and anti-inflammatory functions.

Without stimulating an acute immune response, Butyrate creates an environment that allows the microbiome to exist within humans by reducing the inflammatory capacity of the gut.

Significance of Calcium Butyrate:

When calcium is combined with butyrate in the manufacturing process of Calcium supplements, the immunity-boosting ability of the supplement increases.

As a result, calcium deficiency is eradicated in the human body with an additional boost to immunity. Calcium supplements are also proven to work with more effectiveness and efficiency with the registration of butyrate in the supplements. The addition of butyrate boosts the absorption of calcium and helps to regulate the body’s immunity while it fights the deficiency.

Calcium butyrate should be always administered prior to the consultation with a doctor or a medical expert.

The doctor will always examine the side effects and the benefits before recommending the supplement to the patient. The prescribed dosage should be maintained to avoid any serious effects and the medicine should be taken at a particular time of the day for better remembering. The dosage should be taken on a regular basis to obtain the best results.

There are generally no serious side effects of this supplement. However, if a serious condition arises, then the individual should always consult a doctor or a medical expert. The patient might have to be hospitalized if the condition gets worse.

However, calcium butyrate as a calcium supplement is considered to be good and effective with faster replenishment of the calcium reserves of the human body.

Frequently Asked Questions on: Role of Calcium Butyrate in nutraceutical supplements
What does calcium do for your body?

In order to maintain and build strong bones, the human body requires a proper amount of calcium. In order to function properly, the nerves, muscles, and heart of a human being also need a proper amount of calcium. The protection against high blood pressure, diabetes, and cancer are some of the benefits that Vitamin D alongside calcium can provide beyond just bone health.

What are the disadvantages of calcium?

The benefits of using calcium do not have solid proof or conclusive evidence. There is a risk of taking calcium more than the body permits which can also cause interference with the medications that a person is already into.

Does calcium cause high blood pressure?

There has been an inverse relationship found between blood pressure levels and dietary calcium according to epidemiological studies. Elevated blood pressure may be a result of high calcium intake in certain populations.

What foods are calcium in?

Almonds, canned salmon with bones and sardines, edamame or young green soybeans which are used to make Tofu, which is made with calcium sulfate, winter squash, calcium-fortified orange juice, yogurt, cheese, and dairy products from sheep, goat, and cow, and fortified plant-based milk from rice, soy, almond are some of the food sources that are good in calcium.

What are 4 good sources of calcium?

Dairy foods such as cheese and milk are some good sources of calcium along with green leafy vegetables such as okra and curly kale but not spinach since spinach does contain high levels of calcium but the body cannot digest it all. Soya drinks with added calcium are also a good source of calcium. Anything made with fortified flour and bread is also a good source of calcium. Cereals, juices that are fortified with calcium, bony fishes, dried beans and peas, and dark-green leafy vegetables are some other sources of calcium.

What causes a deficiency of calcium?

Yes, that’s correct! Not getting enough calcium from the diet is indeed the most common cause of calcium deficiency. Other factors that can contribute to calcium deficiency include a diet that is high in protein but low in dairy products and leafy greens, as well as digestive conditions such as celiac disease (gluten intolerance) and lactose intolerance. In these cases, it is important to find alternative sources of calcium through diet or supplements to ensure optimal health and prevent calcium deficiency.

What does calcium do for your body?

Calcium is a crucial mineral for overall health and well-being. It plays a vital role in building and maintaining strong bones, and is also necessary for the proper functioning of the nerves, muscles, and heart. Additionally, calcium in combination with Vitamin D has been shown to provide several other health benefits, including protection against high blood pressure, diabetes, and some types of cancer. To ensure optimal health, it is important to get an adequate amount of calcium from a balanced diet or supplements.

What are the main functions of butyrate?

Butyrate provides up to 90% of the energy requirements of the cells that line the gut of the human body, known as colonocytes, acting as their main fuel. Butyrate helps in the enhancement of the immunity power in the cells present in the gut. By suppressing the activity of specific immune cells, Butyrate functions as an “HDAC inhibitor”, meaning that it performs anticancer and anti-inflammatory functions.


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