Sodium Propionate

Sodium propionate (NaC3H5O2) is the sodium salt of propionic acid, a natural organic acid that is commonly found in some foods and produced by the bacterial fermentation of certain foods. It is used as a food additive and preservative to inhibit the growth of mold and bacteria in food products, such as bread, cheese, and processed meats. Sodium propionate is also used in the production of pharmaceuticals, as well as in some industrial applications. It is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) and is approved for use in food products in many countries around the world.

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It is a white crystalline solid that is soluble in water and has a faint odor of propionic acid. Sodium propionate is commonly used in pharmaceutical formulations as a preservative to prevent the growth of microorganisms.

The molecular structure of sodium propionate consists of a sodium cation (Na+) and a propionate anion (C3H5O2-) which are held together by ionic bonds. The propionate anion is a three-carbon chain with a carboxylic acid group (-COOH) at one end and a methyl group (-CH3) at the other end. It has several synonyms including sodium propionate trihydrate, propionic acid sodium salt, and E281.

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Molecular Formula – C3H5NaO2

Molecular Weight – 96.06 gm/mol

CAS No – 137-40-6

Shelf Life – 36 months

HSN Code – 

Packing Size – 

Storage Condition – Keep Well Closed, protected against light, dry and at room temperature

Additional Info – 

Sl. No. Parameter Specification
1. Description White free flowing powder with occasional friable lumps.
2. Solubility Soluble in water.
3. Identification Positive for Sodium.
4. pH (of a 10% w/v Aqueous Solution) 5.0 – 8.5
5. Loss On Drying (at 105°C for 4hours) NMT 10.0% w/w.
6. Assay (On Dried Basis) NLT 98.0% w/w.

Food preservation: Sodium propionate is commonly used as a food preservative to prevent the growth of mold and bacteria in baked goods, cheese, and other processed foods. It is effective in inhibiting the growth of some common foodborne pathogens, such as Listeria monocytogenes, Salmonella spp., and Escherichia coli.

Bread making: Sodium propionate is sometimes added to bread dough to improve the texture and increase shelf life. It inhibits the growth of mold and bacteria, which can cause bread to spoil quickly.

PH regulator: Sodium propionate is used as a pH regulator in various pharmaceutical formulations to maintain the stability of the active ingredients and prevent degradation. It is also used to adjust the pH of drug solutions for injections.

Buffering agent: This element is used as a buffering agent in oral and topical formulations to maintain the pH of the product within a specific range, which can enhance the stability and efficacy of the active ingredients.

Animal feed: Sodium propionate is sometimes added to animal feed as a mold inhibitor and to improve the palatability of the feed.

Medical applications: Sodium propionate has some medical applications, including as a treatment for fungal infections and as a buffering agent in some medications.

Pesticides: Sodium propionate is used in the production of some pesticides, particularly those used to control fungal and bacterial diseases in crops.


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