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L Ornithine L Aspartate
  • Product Name:

    L Ornithine L Aspartate

  • Molecular Formula:
    C9H19N3O6
  • Molecular Weight:
    265.26 g/mol
  • CAS No.:
    3230-94-2
  • CID Code:
    10220941
  • Shelf Life:
    3 years - 20°C powder
  • ChemSpider ID
    17566
  • UNII No.
    JA08T3B97O

USP of L Ornithine L Aspartate

  • L-Ornithine L-Aspartate is used in the treatment of liver disease.
  • Individuals use L-ornithine-L-aspartate for reduced brain function due to advanced liver disease (hepatic encephalopathy).
  • It is also used for athletic performance and liver cirrhosis.

IUPAC Names of L Ornithine L Aspartate

(2S)-2-aminobutanedioic acid;(2S)-2,5-diaminopentanoic acid

Synonyms of L Ornithine L Aspartate

  • 3230-94-2
  • L-Ornithine-L-aspartate
  • L-Ornithine L-aspartate salt
  • L-Ornithine L-aspartate
  • Ornithine aspartate
  • (S)-2,5-Diaminopentanoic acid compound with (S)-2-aminosuccinic acid (1:1)
  • Ornithine Aseparate
  • (2S)-2-aminobutanedioic acid;(2S)-2,5-diaminopentanoic acid
  • Ornithine Aspartate (L-Ornithine L-Aspartate)
  • (S)-2,5-Diaminopentanoic acid (S)-2-aminosuccinic acid salt
  • L-Ornithine L-aspartate salt, powder

MSDS of L Ornithine L Aspartate

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Chemical Product and Company Identification
  • Product Name: L-Ornithine L- Aspartate
  • Product Code: LOLNL98
  • Relevant identified uses of the substance or mixture and uses advised against: Laboratory chemicals, manufacture of substances
First Aid Measures
  • Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.
  • Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
  • Serious Skin Contact: NA
  • Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
  • Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
  • Most important symptoms and effects, both acute and delayed: The most important known symptoms and effects are described in the labelling.
  • Indication of any immediate medical attention and special treatment needed: Treat symptomatically
Fire-Fighting Measures
  • Suitable Extinguishing Media: Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
  • Large Fire CAUTION: Use of water spray when fighting fire may be inefficient.
  • Unsuitable extinguishing media: Do not scatter spilled material with high pressure water streams
  • Flammability of the Product: May be combustible at high temperature
  • Auto-Ignition Temperature: NA
  • Flash points: NA
  • Flammable Limits: NA
  • Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2…).
  • Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of heat.
  • Explosion Hazards in Presence of Various Substances
    Risks of explosion of the product in presence of mechanical impact: Not available.
    Risks of explosion of the product in presence of static discharge: Not available.
  • Fire Fighting Media and Instructions:
    Small fire: Use DRY chemical powder.
    Large fire: Use water spray, fog or foam. Do not use water jet.
  • Special Remarks on Fire Hazards: Material in powder form, capable of creating a dust explosion. As with most organic solids, fire is possible at elevated temperatures.
  • Special Remarks on Explosion Hazards: Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Exposure Controls / Personal Protection

Engineering Control:
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.

Exposure controls

  • Personal protective equipment: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent Gloves.
  • Eye/face protection: Avoid contact with eyes. Wear safety glasses with side shields (or goggles).
  • Hand protection: The protective gloves to be used must comply with the specifications of EC Directive 89/686/EEC and the standard EN374. Wear protective nitrile rubber gloves.
    Duration of contact: Prolonged exposure
    Glove material: Wear protective nitrile rubber gloves
    Glove thickness: 0.11 mm
    Break through time: 480 minutes
  • Skin and body protection: Wear suitable protective clothing.
  • Respiratory protection: Respiratory protection is not required under normal use conditions. If exposure limits are exceeded or irritation is experienced, ventilation and evacuation may be required.

Personal Protection in case of Large Spill:
Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.

Exposure Limits: NA

General hygiene considerations:
Avoid contact with skin, eyes, or clothing. Do not eat, drink, or smoke when using this product. Wash hands before breaks and after work. Wear suitable gloves and eye protection.

Environmental exposure controls: Do not allow into sewer system, on the ground or into any body of water.

Physical and Chemical Properties
  • Appearance: Solid
  • Melting/freezing point: 198 °C
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Description of L Ornithine L Aspartate

L-ornithine-L-aspartate is broken down by the body to increase the levels of two amino acids: ornithine and aspartic acid. Ornithine and aspartic acid help to reduce levels of a toxic chemical called ammonia in the blood. L-Ornithine L-Aspartate, a combination of two amino acids, works by protecting the liver cells from harmful chemical substances, such as free radicals, thus preventing liver damage.

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Application of L Ornithine L Aspartate

  • Management of Hepatic Encephalopathy: Primarily used in the treatment of hepatic encephalopathy, a decline in brain functions due to severe liver disease, by helping to reduce ammonia levels in the blood.
  • Liver Function Support: Assists in supporting liver function and detoxification processes, especially in individuals with compromised liver health.
  • Ammonia Detoxification: Acts as an ammonia detoxifier by enhancing the urea cycle function, which helps in the conversion of ammonia into urea.
  • Nutritional Supplements: Included in nutritional supplements aimed at promoting liver health and supporting detoxification pathways.
  • Athletic Performance: Sometimes used in sports supplements, as it is believed to reduce ammonia accumulation during prolonged exercise and potentially enhance recovery.
  • Protein Metabolism: Plays a role in protein metabolism, making it beneficial in various health conditions where protein synthesis and breakdown are affected.
  • Fatigue Reduction: May help in reducing physical and mental fatigue, particularly in conditions related to liver dysfunction.
  • Support in Chronic Liver Diseases: Beneficial in managing symptoms and improving quality of life in patients with chronic liver diseases, such as cirrhosis.
  • Adjunct Therapy: Often used as an adjunct therapy in the treatment of conditions that lead to hyperammonemia (excess ammonia in the blood).
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