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Product Name:
Ferric Carboxymaltose
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Molecular Formula:
C24H44FeO25-
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Molecular Weight:
788.4 g/mol
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CAS No.:
9007-72-1
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HSN Code:
30045090
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CID Code:
86278165
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Shelf Life:
3 years - 20°C powder
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DrugBank ID
DB08917
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UNII No.
6897GXD6OE
- USP
- IUPAC Names
- Synonyms
- MSDS
USP of Ferric Carboxymaltose
- Ferric carboxymaltose effectively increases hemoglobin levels and replenish iron stores in patients with iron deficiency anemia.
- FCM permits a much higher single dose of IV iron to be administered over a shorter period.
- FCM shows little anaphylactic shock or hypersensitive reaction.
IUPAC Names of Ferric Carboxymaltose
4-[5-[3,4-dihydroxy-6-(hydroxymethyl)-5-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,5,6-tetrahydroxyhexanoate;iron(3+);oxygen(2-);hydroxide;hydrate
Synonyms of Ferric Carboxymaltose
- Ferric carboxymaltose
- Iron Dextri-Maltose
- iron carboxymaltose
- polynuclear iron (III)-hydroxide 4(R)-(poly-(1->4)-o-alpha-D-glucopyranosyl)-oxy-2(R),3(S),5(R), 6-tetrahydroxy-hexanoate
MSDS of Ferric Carboxymaltose
Download MSDS PDF- GENERAL ADVICE: Never give anything by mouth to an unconscious person. Get medical advice/attention if you feel unwell (show the label where possible).
- IF INHALED: When symptoms occur: Go into open air and ventilate suspected area. Seek medical attention.
- SKIN CONTACT: Remove contaminated clothing. Drench affected area with water for at least 15 minutes. Seek medical attention.
- EYE CONTACT: Rinse thoroughly with plenty of water for 15 minutes and consult a physician.
- IF SWALLOWED: Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
- SUITABLE EXTINGUISHING MEDIA: Water spray, dry chemical, foam, carbon dioxide.
- SPECIAL HAZARDS ARISING FROM THE SUBSTANCE OR MIXTURE: Carbon oxides, nitrogen oxides (NOx), Iron oxides.
- ADVICE FOR FIREFIGHTERS: Wear self-contained breathing apparatus for firefighting if necessary.
- FIRE EXTINGUISHING MEDIA: Use fire-extinguishing media appropriate to the surrounding fire
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet. - FURTHER INFORMATION: No data available.
- APPROPRIATE ENGINEERING CONTROLS: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
- EYE/FACE PROTECTION: Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
- SKIN PROTECTION: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove’s outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
- BODY PROTECTION: Impervious clothing, the type of protective equipment must be selected according to the concentration and amount of the amount of the dangerous substance at the specific workplace.
- EXPOSURE LIMITS: TWA: 1 STEL: 2 (mg(Fe)/m ) [United Kingdom (UK)] TWA: 1 (mg(Fe)/m) from MSHA standard. Consult local authorities for acceptable exposure limits.
- Appearance form: Powder
- Color: Brown to deep brown.
- Odour: No data available
- Solubility: Soluble in warm water.
- Molecular weight: No data available
- pH: 5.0-7.0
- Other safety information: No data available
Description of Ferric Carboxymaltose
Ferric carboxymaltose (FCM) is a ferric iron complex formulated for intravenous administration. It consists of a central core of ferric (Fe3+) ions surrounded by a shell of carboxymaltose molecules, a high-molecular-weight polysaccharide derived from starch. The carboxymaltose ligands are covalently linked to the ferric ions through ester linkages, forming a stable and biocompatible complex. This unique structure offers several advantages. The carboxymaltose shell prevents uncontrolled iron release, minimizing the risk of free radical generation and potential tissue damage. Additionally, the complex size allows for slow and sustained release of iron into the bloodstream, facilitating efficient uptake by transferrin, the iron carrier protein in the body. This controlled release mechanism contributes to the well-tolerated profile of ferric carboxymaltose compared to other intravenous iron formulations. West Bengal Chemical is now a proud patent holder of Ferric Carboxymaltose.
Application of Ferric Carboxymaltose
- Treatment of Iron Deficiency Anemia
- Inflammatory Bowel Disease (IBD)
- Chronic Kidney Disease
Applications in medical fields
- Iron Deficiency Anemia Treatment: Used primarily for the treatment of iron deficiency anemia.
- Chronic Kidney Disease: Particularly beneficial for patients with chronic kidney disease.
- Rapid Iron Replenishment: Provides a fast and efficient method for replenishing.
- Postpartum Anemia: Helping new mothers recover iron levels quickly.
- Chronic Heart Failure: Used to manage iron deficiency in patients with chronic heart failure.
- Inflammatory Bowel Disease: Suitable for patients with inflammatory bowel disease (IBD).
Nutraceutical Uses
Iron Supplementation: Included in specialized dietary supplements aimed at individuals with specific iron needs
Enhanced Bioavailability: Offers a highly bioavailable form of iron, ensuring better absorption and efficacy
General Health and Wellbeing: Supports overall health by maintaining adequate iron levels, which are essential for numerous bodily functions.
Energy Levels: Helps boost energy levels by improving oxygen transport and reducing fatigue causedby iron deficiency.
Athletic Performance: Beneficial for athletes who require optimal iron levels for peak performanceand recovery.
Side effects:
Ferric carboxymaltose may cause various side effects if not advisably taken. Here are the key side effects:
- Nausea
- Vomiting
- Headache
- Dizziness
Suppliers of Ferric Carboxymaltose include major pharmaceutical company like West Bengal Chemical Industries Limited.
Another name for Ferric Carboxymaltose is Injectafer (in the USA) or Ferinject (in other markets).
Ferric Carboxymaltose is composed of a ferric iron complex with a carbohydrate polymer (Carboxymaltose) designed for intravenous iron supplementation.
Ferric carboxymaltose replenishes iron stores in the body, helping to treat iron deficiency anemia by increasing hemoglobin levels and improving symptoms associated with iron deficiency.
Ferric Carboxymaltose is classified as an intravenous iron replacement therapy.
Ferric Carboxymaltose is typically a dark brown, opaque solution.
