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Product Name:
Ferric Citrate / Ferric Citrate Hydrate
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Molecular Formula:
C6H5FeO7 x H20
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Molecular Weight:
244.94 g/mol
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CAS No.:
2338-05-8
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HSN Code:
2918
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CID Code:
61300
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Shelf Life:
3 years - 20°C powder
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ATC Code (WHO)
V03AE08, B03AB01
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ChemSpider ID
55239
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UNII No.
63G354M39Z
- USP
- IUPAC Names
- Synonyms
- MSDS
USP of Ferric Citrate / Ferric Citrate Hydrate
A solvent free process for preparation of pharmaceutical grade Ferric Citrate characterized in that oxidizing aqueous mix of Citric Acid Monohydrate and Iron Powder in a molar ratio from about 0.8 to 1.5 until the Ferric content reaches 21-22% and Ferrous content less than 1% on dried basis.
IUPAC Names of Ferric Citrate / Ferric Citrate Hydrate
iron(3+) 2-hydroxypropane-1,2,3-tricarboxylate
Synonyms of Ferric Citrate / Ferric Citrate Hydrate
- FERRIC CITRATE
- Iron(III) citrate
- Iron citrate
- ferrum citricum
- ferric citrate anhydrous
- Iron citrate, FeC6H5O7
- Iron(III) citrate tribasic
- Iron(III)-citrate
- Iron (III) citrate
- ferric citrate dihydrate
- ferric citrate hydrate
- ferric citrate iron(+3) salt
- ferric citrate trihydrate
- ferric-citric acid
- iron(III) citrate
- 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, iron(3+) salt (1:1)
- Iron, (hydrogen citrato(3-))-
- Citric acid, iron salt
- Citric acid, iron(3+) salt (1:1)
- iron(iii)citrate
- iron(3+) citrate
- 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, iron salt
- 2-hydroxy-1,2,3-propanetricarboxylic acid iron salt
- 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, iron(3+) salt
- Iron 2-hydroxy-1,2,3-propanetricarboxylate
- Fe(3+)-citrate
- iron(3+) 2-hydroxypropane-1,2,3-tricarboxylate
- iron(III) 2-hydroxypropane-1,2,3-tricarboxylate
- Ferric citrate
- Iron(III) Citrate (Technical Grade)
- Citric acid, iron(3+) salt
- FERRICCITRATE
- 2-hydroxypropane-1,2,3-tricarboxylate;iron(3+)
- (2-hydroxypropane-1,2,3-tricarboxylato(3-)-kappa(3)O(1),O(2),O(3))iron
- Citric acid,iron(3+)salt
- 2-hydroxypropane-1,2,3-tricarboxylate; iron(3+)
- Iron(III) citrate; Iron citrate
- iron(3+); 2-oxidanylpropane-1,2,3-tricarboxylate
- 2338-05-8 (hydrate), 3522-50-7 (anhydrous)
- 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, iron salt (1:?)
- Ferric citrate monohydrate
- Iron(III) citrate hydrate
- Iron(III) citrate tribasic monohydrate
- ferric citrate hydrate
- 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, iron(3+) salt, hydrate (1:1:1)
- 2-hydroxypropane-1,2,3-tricarboxylate;iron(3+);hydrate
- 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, iron(3+) salt (1:1), monohydrate
- Iron(iii)citrate hydrate,98
- iron(III) citrate monohydrate
- IRON(3+) CITRATE HYDRATE
- iron(3+) 2-hydroxypropane-1,2,3-tricarboxylate hydrate
- 2-Hydroxy-1,2,3-propanetricarboxylic Acid, Iron(3+) Salt (1:1); Citric Acid, Iron(3+) Salt (1:1) (8CI); Fe(III)-Citrate Complex (1:1); Ferric Citrate;
MSDS of Ferric Citrate / Ferric Citrate Hydrate
Download MSDS PDF- If inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration.
- In case of skin contact: Wash off with soap and plenty of water.
- In case of eye contact: Flush eyes with water as a precaution.
- If swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water.
- Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section - Indication of any immediate medical attention and special treatment needed: No data available
- Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
- Special hazards arising from the substance or mixture: Carbon oxides, Iron oxides
- Advice for firefighters: Wear self-contained breathing apparatus for firefighting if necessary.
- Further information: No data available
- Control parameters: Not available
- Exposure controls: Not available
- Appropriate engineering controls: General industrial hygiene practice.
- Eye/face protection: Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
- Skin protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove’s outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
- Body Protection: Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
- Respiratory protection: Respiratory protection is not required. Where protection from nuisance le (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
- Control of environmental exposure: Do not let product enter drains.
- Appearance Form: Greenish brown to brown hygroscopic powder.
- Odour: No data available
- Melting point/freezing point: No data available
- Initial boiling point and boiling range: No data available
- Water solubility: Freely soluble in water
- Decomposition temperature: No data available
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Description of Ferric Citrate / Ferric Citrate Hydrate
Ferric citrate (FC) is world’s latest phosphate binder having much higher phosphate binding capacity, simultaneously it replenishes iron to CKD patients. Patent holder for “Solvent Free, Cost-Effective Process for Preparation of Ferric Citrate”
The phosphate-binding capacity of ferric citrate is estimated to be approximately 84.8 to 87.9 mg of phosphorus per gram of elemental ferric iron and 19.1 to 19.8 mg of phosphorus per gram of ferric citrate.
Application of Ferric Citrate / Ferric Citrate Hydrate
- Treatment of Hyperphosphatemia in Kidney Disease
- Source of dietary iron
- Management of Anemia in Chronic Kidney Disease
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