API & Fine Pharmaceutical Manufacturer in India
Ferric Maltol
  • Product Name:

    Ferric Maltol

  • Molecular Formula:
    C18H15FeO9
  • Molecular Weight:
    431.2 g/mol
  • CAS No.:
    33725-54-1
  • HSN Code:
    29329900
  • CID Code:
    169535
  • Shelf Life:
    3 years - 20°C powder
  • ATC Code (WHO)
    B03AB10
  • DrugBank ID
    DB876
  • Chem Spider ID
    148265
  • UNII No.
    MA10QYF1Z0

USP of Ferric Maltol

  • Low dose of iron is required due to its higher absorption.
  • It can be use as a prophylaxis after the iron infusion.

IUPAC Names of Ferric Maltol

Iron (3+) tris(2-methyl-4-oxo-4H-pyran-3-olate)

Synonyms of Ferric Maltol

  • Ferric maltol
  • 33725-54-1
  • Iron (III) maltol
  • iron maltol
  • iron(3+);2-methyl-4-oxopyran-3-olate
  • Iron(III) 2-methyl-4-oxo-4H-pyran-3-olate
  • Iron, tris[3-(hydroxy-kO)-2-methyl-4H-pyran-4-onato-kO4]-
  • Iron, tris(3-hydroxy-2-methyl-4H-pyran-4-onato-O3,O4)-
  • maltol ferrico
  • maltol ferrique
  • ferricum maltolum
  • TRIS(3-(HYDROXY-kappaO)-2-METHYL-4H-PYRAN-4-ONATO-kappaO4)IRON(III)
  • Tris[3-(hydroxy-kappaO)-2-methyl-4H-pyran-4-onato-kappaO4]iron(III)
  • Ferric maltol

MSDS of Ferric Maltol

Download MSDS PDF
First Aid Measures

INHALATION: Chemical Stability: Stable under normal conditions of storage and Eyes: If irritation or redness develops from exposure to fumes generated during handling of hot-melt processing operations, move victim away from exposure and into fresh air. Flush eyes with clean water.

INGESTION: If Conditions to Avoid: Avoid all possible sources of ignition. Irritation or redness persists, seek medical attention. For contact with Incompatible Materials: Avoid contact with strong oxidizing agents.

SKIN CONTACT: The molten material, gently open eyelids and flush affected area with Hazardous Decomposition Products: Combustion can yield major amounts of oxides of carbon and minor amounts of oxides of sulfur and cold water. Seek immediate medical attention.

EYE CONTACT: Skin: For contact with molten material, leave material on skin and flush or immerse affected area using cold water. Seek medical attention Hazardous Polymerization: Will not occur.

Fire-Fighting Measures
  • FLAMMABILITY OF THE PRODUCT: May be combustible at high temperature.
  • AUTO IGNITION TEMPERATURE: Not available.
  • FLASH POINTS: Not available.
  • PRODUCTS OF COMBUSTION: These products are carbon oxides (CO, CO2). Some metallic oxides.
  • FIRE HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES: Slightly flammable to flammable in presence of heat. Nonflammable in presence of shocks.
  • EXPLOSION HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES: Slightly explosive in presence of open flames and sparks. Non-explosive in presence of shocks.
Exposure Controls / Personal Protection
  • ENGINEERING CONTROLS: None required when working with the solid material. If airborne concentrations of wax fumes, generated from molten wax, are expected, a NIOSH/MSHA approved air purifying respira-10. Toxicological Information tor with a dust/mist/fume filter may be used. No definitive information available on carcinogenicity.
  • PERSONAL PROTECTION: Not normally required for solid material. The use of thermally resistant gloves is recommended when there is a potential for exposure to molten wax. Disposal Consideration This material, if discarded as produced, is not a RCRA listed.
  • PERSONAL PROTECTION IN CASE OF A LARGE SPILL: Approved eye protection to safeguard against potential eye contact, irritation, or injury is recommended. A characteristic hazardous waste. Use which results in chemical or source of clean water should be available in the work area for flushing physical change or contamination may subject it to hazardous waste eyes and skin handling this product.
  • EXPOSURE LIMITS: Consult local authorities for acceptable exposure limits.
Physical and Chemical Properties
  • APPEARANCE FORM: Deep brown, free flowing powder.
  • VAPOR PRESSURE AT 35°C: No information found.
  • RELATIVE DENSITY: 1.3
  • VAPOR DENSITY (AIR = 1): No information found.
  • ODOUR: No information found.
  • SOLUBILITY: Soluble in Chloroform Soluble in Alcohol Soluble in Propylene glycol
  • Melting / Freezing Point: about 300°C literature.
  • PH (5% w/v Solution): 6.0 – 9.5
  • Molecular Weight: No information found.
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Description of Ferric Maltol

Ferric maltol is a chemical compound used as an iron supplement. Ferric maltol, formally named (3-hydroxy-2-methyl-4-pyronato)iron(III), is a coordination complex containing iron(III) centrally chelated by a maltol (3-hydroxy-2-methyl-4-pyrone) ligand. This complexation enhances the solubility and bioavailability of iron compared to inorganic iron salts. The iron center exhibits octahedral geometry, coordinated with six oxygen atoms – three from the maltol ligand and three water molecules. This unique structure allows for controlled iron release and minimizes the gastrointestinal side effects often associated with traditional iron supplements. West bengal chemical is now proud patent holder of Ferric Maltol.

Application of Ferric Maltol

  • Gastrointestinal Disorders
  • Treatment of Iron-Deficiency Anemia
  • Increased Iron Absorption
  • Reducing Fatigue and Anemia Symptoms

Medical uses/benefits of Ferric Maltol

  • Iron Deficiency Anemia (IDA): Used to treat iron deficiency anemia in adults with chronic inflammatory diseases like in inflammatory bowel disease (IBD)
  • Chronic Kidney Disease (CKD): Used in patients with CKD who are non-dialysis dependent
  • Better Tolerability: Have better gastrointestinal tolerability compared to traditional oral iron supplements.
  • Reduces side effects like nausea, constipation, and abdominal pain
  • Enhanced Absorption: Allows for better absorption of iron in the gastrointestinal tract
  • Improve iron levels more efficiently

Oral dosage form (capsules):

  • For adults—30 mg twice a day for at least 4 months.
  • For children—Use and dose must be determined by healthcare professionals.

Side effects

Common side effects of Ferric Maltol include nausea, abdominal pain, and changes in stool color.  More severe reactions can involve hypersensitivity and iron overload. So, it is always advisable to take its dosage as per doctor’s suggestion.

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Frequently Asked Questions on: Ferric Maltol
Who is the manufacturer of ferric maltol in India?

While India boasts many API manufacturers, West Bengal Chemical Industries stands out as a top Ferric Maltol exporter. Our product delivers efficient iron absorption with superior tolerability, minimizing the side effects often associated with iron supplements.

What is the melting point of ferric maltol?

The melting point of ferric maltol is approximately 302.8°C (±0.5°C)​.

What are the advantages of ferric maltol?

Ferric maltol offers various advantages, particularly for patients with iron deficiency anemia. Here are the key benefits:

  • Improved Tolerability
  • Enhanced Absorption
  • Lower Risk of Iron Overload
  • No Need for Acidic Environment
How long does ferric maltol take to work?

Ferric maltol can start to show improvements in iron levels and symptoms of iron deficiency anemia relatively quickly.

When was ferric maltol approved?

Ferric maltol received approval for medical use in the United States on July 25th, 2019.

Is ferric maltol safe?

Yes! Ferric Maltol is safe if it takes as prescribed

What is the Colour of ferric maltol?

Ferric maltol, as a substance, is typically reddish-brown in color.

What is the generic name for ferric maltol?

The generic name for ferric maltol is simply ferric maltol.

Is WBCIL's ferric maltol approved?

Yes! WBCIL’s ferric maltol is approved.

Ferric Maltol uses and benefits

Uses of Ferric Maltol in Pharmaceutical Industries:

  • Treatment of Iron Deficiency Anemia (IDA): Effective in replenishing iron stores and improving hemoglobin levels, especially in patients with chronic conditions.
  • Chronic Kidney Disease (CKD): Provides a well-tolerated option to manage anemia, maintaining adequate iron levels.
  • Inflammatory Bowel Disease (IBD): Ideal for treating IBD-related anemia due to its gentle action on the gastrointestinal tract.
  • Superior Bioavailability: Requires lower doses for therapeutic effects, reducing the risk of iron overload.
  • Minimized Side Effects: Reduces gastrointestinal irritation, improving patient compliance and comfort.
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