API & Fine Pharmaceutical Manufacturer in India
Calcium Citrate Malate
  • Product Name:

    Calcium Citrate Malate

  • Molecular Formula:
    C24H34Ca6O35
  • Molecular Weight:
    1123 g/mol
  • CAS No.:
    142606-53-9
  • HSN Code:
    29181590
  • CID Code:
    156596391
  • Shelf Life:
    3 years - 20°C powder
  • UNII No.
    4BBS3A53GJ

USP of Calcium Citrate Malate

  • Calcium absorption is better than calcium citrate.
  • A smaller dose calcium citrate malate provides the same amount of absorbable calcium as other calcium compound.

IUPAC Names of Calcium Citrate Malate

hexacalcium;2-hydroxybutanedioate;2-hydroxypropane-1,2,3-tricarboxylate;hexahydrate

Synonyms of Calcium Citrate Malate

  • CCM
  • Calcium citrate malate [USP-RS]
  • Calcium citrate malate [WHO-DD]
  • Calcium citrate malate (6:2:3), hexahydrate
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Description of Calcium Citrate Malate

Calcium Citrate Malate is a water-soluble calcium supplement. It is the calcium salt of citric acid and malic acid with similar proportion  of citric acid and malic acid. It is available as USP & IP.

Application of Calcium Citrate Malate

Treats conditions arising from low calcium levels like:

  • Osteoporosis (bone loss).
  • Osteomalacia/rickets (weak bones).
  • Hypoparathyroidism (decreased parathyroid gland activity).
  • Latent tetany (a specific muscle disease).
  • Bone Health Supplement: CCM is a commonly prescribed supplement for the prevention and treatment of osteoporosis and other conditions that require increased calcium intake.
  • Adjunct in Antacid Therapy: It’s used as an ingredient in antacid formulations to help alleviate symptoms of indigestion while providing calcium.
  • Nutritional Fortification: CCM is used to fortify various food products to enhance their calcium content.
  • Calcium Deficiency: It is used to treat conditions caused by low blood calcium levels, such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and certain muscle diseases (latent tetany).
  • Pregnancy and Lactation: It provides an important source of dietary calcium for pregnant and breastfeeding women to support the development of the fetus and the nutritional needs of the mother.
  • Dental Health: Calcium is essential for maintaining dental health, and CCM supplements may be recommended to prevent tooth decay.
  • Renal Osteodystrophy Management: Patients with chronic kidney disease often develop renal osteodystrophy, and CCM is used to manage calcium levels in such patients.
  • Muscle Contraction: It aids in the proper functioning of nerves and muscle cells, including the heart muscle.
  • Blood Coagulation: Calcium plays a crucial role in blood clotting, and CCM can be part of the management strategy for patients with bleeding disorders that are related to calcium deficiency.
  • Drug Formulations: CCM is used in various pharmaceutical formulations due to its favorable bioavailability and sustained-release properties.

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