API & Fine Pharmaceutical Manufacturer in India
Calcium Citrate Malate
  • Product Name:

    Calcium Citrate Malate

  • Molecular Formula:
    C24H34Ca6O35
  • Molecular Weight:
    1123 g/mol
  • CAS No.:
    142606-53-9
  • HSN Code:
    29181590
  • CID Code:
    156596391
  • Shelf Life:
    3 years - 20°C powder
  • UNII No.
    4BBS3A53GJ

USP of Calcium Citrate Malate

  • High bioavailability
  • Calcium citrate & malic acid team up for superior calcium uptake
  • Fights osteoporosis & weak bones with high absorption.
  • Malic Acid improves gut tolerance.

IUPAC Names of Calcium Citrate Malate

hexacalcium;2-hydroxybutanedioate;2-hydroxypropane-1,2,3-tricarboxylate;hexahydrate

Synonyms of Calcium Citrate Malate

  • CCM
  • Calcium citrate malate [USP-RS]
  • Calcium citrate malate [WHO-DD]
  • Calcium citrate malate (6:2:3), hexahydrate

MSDS of Calcium Citrate Malate

Download MSDS PDF
First Aid Measures
  • GENERAL ADVICE: Consult a physician. Show this safety data sheet to the doctor in attendance
  • IF INHALED: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
  • SKIN CONTACT: Wash off with soap and plenty of water. Consult a physician.
  • EYE CONTACT: Flush eyes with water as precaution.
  • IF SWALLOWED: Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Fire-Fighting Measures
  • SUITABLE EXTINGUISHING MEDIA: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  • SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS: Wear self-contained breathing apparatus for firefighting if necessary.
Exposure Controls / Personal Protection
  • HYGIENE MEASURES: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
  • RESPIRATORY PROTECTION: Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
  • HAND PROTECTION: The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Handle with gloves.
  • EYE PROTECTION: Safety glasses with side-shields conforming to EN166.
  • SKIN AND BODY PROTECTION: Choose body protection according to the amount and concentration of the dangerous substance at the workplace.
Physical and Chemical Properties
  • Appearance form: Powder
  • Color: White to almost white
  • Odour: No data available
  • Solubility: No data available
  • Molecular weight: No data available
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Description of Calcium Citrate Malate

Calcium citrate malate (CCM) is a calcium supplement formulated for enhanced bioavailability. Calcium citrate malate is slightly hygroscopic and has a fine, free-flowing texture. It comprises a variable composition chelate, combining calcium cations (Ca²⁺) with citric acid (C₆H₇O₇) and malic acid (C₄H₆O₅) molecules. The specific ratio of these organic acids to calcium can vary depending on the manufacturing process.

This chelation with organic acids is the key factor influencing CCM’s superior absorption compared to other calcium salts. We provide the highest quality Calcium citrate malate, backed by stringent GMP (Good Manufacturing Practice) and ISO guidelines. Emerging research suggests a potentially lower kidney stone risk compared to calcium citrate alone. With over 62 years of experience as one of India’s most reliable API manufacturers, our team possesses the expertise to deliver calcium citrate malate that meets your specific needs and requirements.

What is calcium citrate malate formula? 

Calcium citrate malate is a calcium supplement that combines citric acid and malic acid. Its exact formula can vary depending on the specific proportions of each component.  

However, a common representation of its formula is: C24H34Ca6O35

This formula indicates that it contains six calcium ions (Ca²⁺), 24 carbon atoms, 34 hydrogen atoms, and 35 oxygen atoms.

Application of Calcium Citrate Malate

As Vitamin D3

  • Bone Health: Calcium citrate malate combined with Vitamin D3 promotes stronger bones and helps prevent osteoporosis by improving calcium absorption.
  • Enhanced Calcium Absorption: The addition of Vitamin D3 ensures better absorption of calcium from the intestines, boosting the efficiency of calcium citrate malate.

Uses of calcium citrate malate

Pharmaceutical uses:

  • Calcium Fortification: Incorporated into medications targeting calcium deficiency disorders, with its superior absorption compared to other calcium salts.
  • Elderly Care: Commonly used in formulations designed for older adults, helping combat bone density loss.

Nutraceutical and Healthcare Supplements

  • Bone Health: Widely used in supplements to prevent and treat osteoporosis due to its high bioavailability.
  • Vitamin D3 Synergy: Often combined with Vitamin D3 to enhance calcium absorption for optimal bone and muscle health.

Food & Beverage Industry

  • Fortified Foods: Added to juices, dairy products, and non-dairy alternatives (like almond milk) to enhance calcium and vitamin content.
  • Functional Foods: Used in health-focused products for bone and heart health.
Sports Nutrition

Performance Supplements: Included in sports supplements to support muscle contraction, nerve function, and overall physical recovery.

Benefits of Calcium Citrate Malate

  • Boosts Bone Strength: Calcium citrate malate is known for its exceptional ability to strengthen bones, making it a key player in preventing osteoporosis and bone fractures.
  • Highly Absorbable: Unlike other calcium supplements, it’s absorbed efficiently by the body, even on an empty stomach, ensuring maximum benefits.
  • Supports Muscles & Joints: It helps maintain proper muscle contraction and joint flexibility, reducing the risk of cramps and stiffness.
  • Corrects Calcium Deficiency: Effectively addresses low calcium levels, preventing associated issues like brittle bones and muscle weakness.
  • Promotes Heart Health: Regulates calcium levels to support normal heart rhythm and cardiovascular function.
  • Dental Health: Helps in maintaining healthy teeth by strengthening enamel.
  • Muscle and Nerve Function: Supports normal muscle function and nerve transmission.
  • Cardiovascular Health: Assists in maintaining normal heart function by regulating calcium levels in the blood.
  • Convenience: It’s often used in supplements for efficient calcium and Vitamin D3 delivery.
If you are interested on Calcium Citrate Malate, then
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