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Calcium Citrate
  • Product Name:

    Calcium Citrate

  • Molecular Formula:
    C12H10Ca3O14
  • Molecular Weight:
    498.4 g/mol
  • CAS No.:
    5785-44-4
  • HSN Code:
    30049099
  • CID Code:
    13136
  • Shelf Life:
    3 years - 20°C powder
  • DrugBank ID
    DB11093
  • ChemSpider ID
    12584
  • UNII No.
    86117BWO7P, MLM29U2X85 (tetrahydrate)

USP of Calcium Citrate

Calcium citrate shows better absorption and used as  calcium supplementation.

IUPAC Names of Calcium Citrate

  • tricalcium;2-hydroxypropane-1,2,3-tricarboxylate
  • 2-hydroxy-1,2,3-propane-tricarboxylic acid calcium salt (2:3)

Synonyms of Calcium Citrate

  • Calcium Citrate
  • Tricalcium Dicitrate
  • Tricalcium Citrate
  • Calcium Citrate
  • Calcium Citrates
  • Citrate, Calcium
  • Citrates, Calcium
  • Tricalcium dicitrate
  • Calcium citrate, tribasic
  • Calcium Citrate anhydrous
  • 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, calcium salt (2:3)
  • Calcium 2-hydroxy-1,2,3-propanetricarboxylate (3:2)
  • tricalcium;2-hydroxypropane-1,2,3-tricarboxylate
  • tricalcium citrate tetrahydrate
  • 2-Hydroxy-1,2,3-propanetricarboxylic acid calcium salt (2:3)
  • Tribasic calcium citrate
  • Tricalcium dicitrate tetrahydrate
  • Citric acid, calcium salt (2:3)
  • calcium citrate tribasic
  • tricalcium bis(citric acid)
  • calcium 2-hydroxypropane-1,2,3-tricarboxylate (3:2)
  • citric acid calcium salt (2:3)
  • tricalcium bis(2-hydroxypropane-1,2,3-tricarboxylic acid)
  • calcium 2-hydroxypropane-1,2,3-tricarboxylate (3/2)

MSDS of Calcium Citrate

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First Aid Measures
  • General advice: Consult a physician. Show this safety data sheet to the doctor in attendance.
  • If inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
  • In case of skin contact: Wash off with soap and plenty of water. Consult a physician.
  • In case of eye contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
  • If swallowed: Never give anything by mouth to an unconscious person. Rinse mouth with water.
  • Most important symptoms and effects, both acute and delayed: The most important known symptoms and effects are described in the labeling and/or in section 11
  • Indication of any immediate medical attention and special treatment needed: No data available
Fire-Fighting Measures
  • Flammability of the Product: May be combustible at high temperature.
  • Auto-Ignition Temperature: Not available.
  • Flash Points: CLOSED CUP: Higher than 93.3°C (200°F).
  • Flammable Limits: Not available.
  • Products of Combustion: Some metallic oxides.
  • Products of Decomposition: acetone and calcium carbonate
  • Fire Hazards in Presence of Various Substances: Not available.
  • Explosion Hazards in Presence of Various Substances: Risks of explosion of the product in presence of mechanical impact/ static discharge: Not available.
  • Fire Fighting Media and Instructions:
    SMALL FIRE: Use DRY chemical powder.
    LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
  • Special Remarks on Explosion Hazards: Not available.
Exposure Controls / Personal Protection
  • Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
  • Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
  • Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
  • Exposure Limits: Not available.
Physical and Chemical Properties
  • Appearance Form: White free flowing powder, with occasional friable lump.
  • Form: Solid, powder in nature
  • Color: White
  • Molecular weight: 570.49 gm/mol
  • Solubility: Slightly soluble in water, freely soluble in diluted 3(N) HCl & in diluted 2(N) Nitric acids, insoluble in alcohol.
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Description of Calcium Citrate

Calcium citrate is the calcium salt of citric acid. It is insoluble in nature. Calcium citrate has 22% of elemental calcium.

Application of Calcium Citrate

  • Act as a phosphate binder to reduce phosphate absorption in the digestive tract.
  • Used as an active ingredient in antacid medications.
  • Used as a buffer agent in pharmaceutical formulations to maintain the desired pH levels
  • Chelating agent to complex with metal ions, which can improve the stability and bioavailability of certain drug.
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