Sucroferric Oxyhydroxide

Description of Sucroferric Oxyhydroxide

Sucroferric oxyhydroxide works by lowering the amount of phosphorus the body absorbs from food. It belongs to a group of medications called phosphate binders.

Application of Sucroferric Oxyhydroxide

• Phosphate Binder: It is primarily used as a phosphate binder in patients with chronic kidney disease (CKD) on dialysis. Sucroferric oxyhydroxide helps to reduce serum phosphate levels in these patients.
• Hyperphosphatemia Management: Effective in the treatment of hyperphosphatemia (high phosphate levels in the blood) in adult patients with CKD on hemodialysis or peritoneal dialysis.
• Lowering Phosphate Absorption: It works by binding to dietary phosphate in the gastrointestinal tract, thereby reducing phosphate absorption into the bloodstream.
• Reducing Pill Burden: Due to its high phosphate binding capacity, it can be taken in lower doses compared to other phosphate binders, which potentially reduces the pill burden for patients.
• Improving Mineral & Bone Disorder in CKD: By controlling phosphate levels, it contributes to the management of mineral and bone disorder associated with chronic kidney disease.
• Non-Calcium, Non-Aluminum Based Binder: Offers an alternative for patients who may have complications or contraindications with calcium or aluminum-based phosphate binders.
• Gastrointestinal Tolerability: Generally well-tolerated with a lower incidence of gastrointestinal side effects compared to some other phosphate binders.
• Research in Non-Dialysis CKD Patients: While primarily used in dialysis patients, there is ongoing research into its effectiveness and safety in CKD patients who are not yet on dialysis.
• Potential Cardiovascular Benefits: By managing phosphate levels, it may help reduce the risk of cardiovascular issues, which are common complications in patients with CKD.